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M9630244.TXT
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1996-02-27
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34 lines
Document 0244
DOCN M9630244
TI Primary adrenal leiomyosarcoma in a man with acquired immunodeficiency
syndrome (AIDS). Further evidence for an increase in smooth muscle
tumors related to Epstein-Barr infection in AIDS.
DT 9603
AU Zetler PJ; Filipenko JD; Bilbey JH; Schmidt N; Department of Pathology
and Laboratory Medicine, St Paul's; Hospital, University of British
Columbia, Vancouver, Canada.
SO Arch Pathol Lab Med. 1995 Dec;119(12):1164-7. Unique Identifier :
AIDSLINE MED/96104661
AB We report a rare primary adrenal leiomyosarcoma in a 30-year-old, human
immunodeficiency virus--positive man. This is, we believe, the third
documented case in the English literature of this tumor in this site,
and the first to be reported in an adult male with acquired
immunodeficiency syndrome. The smooth muscle origin of this tumor was
apparent by routine microscopy and confirmed by positive immunostaining
for smooth muscle actin. The patient is presently well and shows no
evidence of recurrence 20 months after surgery. The present findings are
discussed with reference to the reported rising incidence of smooth
muscle tumors in human immunodeficiency virus--infected patients and the
associated etiologic role of Epstein-Barr virus in the pathogenesis of
these tumors.
DE Acquired Immunodeficiency Syndrome/*COMPLICATIONS Adrenal Gland
Neoplasms/*ETIOLOGY/PATHOLOGY Adult Case Report Herpesviridae
Infections/*COMPLICATIONS Herpesvirus 4, Human/ISOLATION & PURIF Human
Leiomyosarcoma/*ETIOLOGY/PATHOLOGY Magnetic Resonance Imaging Male
RNA, Messenger/ANALYSIS Tumor Virus Infections/*COMPLICATIONS JOURNAL
ARTICLE REVIEW REVIEW OF REPORTED CASES
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).